San Francisco vs St. Louis
Cost of living comparison — C2ER 2024-2025 data
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St. Louis is 61% cheaper than San Francisco overall.San Francisco has a cost of living index of 225 vs St. Louis at 88 (national average = 100). The biggest difference is housing — San Francisco costs 82% more.

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San Francisco
CA
225
COLI index
VS
St. Louis
MO
88
COLI index
Category Breakdown
| Category | San Francisco | St. Louis | Difference |
|---|---|---|---|
| Overall COLI | 225 | 88 | -61% |
| Housing | 435 | 80 | -82% |
| Groceries | 119 | 101 | -15% |
| Transport | 118 | 100 | -15% |
| Healthcare | 108 | 102 | -6% |
| Utilities | 125 | 107 | -14% |
Median 1BR Rent
San Francisco
$3,200/mo
St. Louis
$1,050/mo
Median Home Price
San Francisco
$1,290,000
St. Louis
$205,000
Median Household Income
San Francisco
$136,689
St. Louis
$48,438
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Last updated: June 2026
Methodology: Cost of living indices from C2ER Cost of Living Index 2024-2025. Rent data from Zillow December 2024. Home price data from Zillow Home Value Index December 2024. Household income from US Census Bureau ACS 2023. National average COLI = 100. Data updated annually.